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We couldn't get cream, so we used yoghurt as a substitute.
a milk/sugar/meat substitute
a synthetic substitute for rubber
Rituals and superstitions may become a substitute for a religious life.
Of course a pet is a poor substitute for human companionship.
Feeling sorry for someone is no substitute for love.
This is the British English definition of substitute. View American English definition of substitute.
the amount of money that a business makes or loses