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Instead of using silicon, they have substituted a more flexible material.
You can substitute chicken for beef if you don't like red meat.
The objective is to substitute real democratic politics for conflict and violence.
She suggested that we take out the word 'demand' and substitute 'request'.
Police investigators substituted Palmer's bag for a similar one, then followed him to his hideout.
Owing to the high insurance costs, the original painting has been substituted with a copy.
This is the British English definition of substitute. View American English definition of substitute.