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game-changer

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noun [countable] game-changer pronunciation in American English /ˈɡeɪmˌtʃeɪndʒər/ 
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singulargame-changer
pluralgame-changers
  1. something that completely changes the way something is done, thought about, or made

    Climate change is the most potent game-changer for business over the next century.

    Synonyms and related words for this sense of game-changer

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