Definition from macmillandictionary.com
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The wood is coated with a special substance that protects it from the sun.
Some workers had developed cancer after exposure to radioactive substances.
Heroin is an addictive substance.
The campus is a substance-free environment.
Her comments added substance to the debate.
The band is all glitz and no substance.
The agency hasn’t accomplished anything of substance for years.
He refused to discuss the substance of the meetings.
There is no substance to his accusations.
Their appearance together gave substance to the rumours of their imminent marriage.