Definition from macmillandictionary.com
Your browser doesn’t support HTML5 audio
The house was quiet again, after the noise of their departure.
an early departure from London
a 10 o’clock departure
The next departure for New York will be at 11.00.
Things had got worse since his departure from head office.
Being a teacher is a totally new departure for me.
This is a significant departure from their earlier policies.