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irritation

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noun British English pronunciation: irritation /ˌɪrɪˈteɪʃ(ə)n/ 
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singularirritation
pluralirritations
  1. 1
    [uncountable] a feeling of being annoyed or impatient

    He could barely contain his irritation at their rudeness.

  2. 2
    [countable/uncountable] a painful feeling in a part of the body, often with red skin or swelling

    drugs that can cause stomach irritation

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