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Word of the Week Archive
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living
bandage noun [C] / l v
b nd d /
a bandage made from skin cells
grown from a sample of the patient’s skin
‘A former prisoner of war, now in his 80s,
who developed ulcers on his legs while interned in a
Japanese camp, was also successfully treated with the “living
bandage” after failing to respond to various
treatments over the past 60 years.’
(The
Scotsman, 27th April 2004)
We’ve all seen the science fiction movies where ailing
superheroes undergo a fantastic regeneration, their wounds
miraculously disappearing without trace. Although medical
advances can’t quite yet make us as indestructible as the
characters played by Arnold Schwarzenegger, scientists have
recently perfected a revolutionary treatment which dispenses
with conventional bandages and heals wounds via the
regeneration of a patient’s own skin cells. This technique
is known as a living
bandage.
In order to develop a living
bandage, skin cells are scraped from a patient, often
from the thigh area, and cultured in a laboratory on
specially designed plastic discs. The skin cells multiply
and form a living
bandage of a patient’s own skin which is applied as a
patch at the site of the wound, triggering new layers of
skin growth. By using the patient’s own skin, rejection
issues are eliminated, allowing natural healing to take
place rapidly.
Every year in the UK, around three million people suffer
serious wounds, among them a high proportion of severe burn
injuries. The living bandage could revolutionise the treatment of burns, as
illustrated by a trial on a nine-year-old boy who, suffering
from burns on his back and legs, showed evidence of healing
within just three days of undergoing the treatment. Living
bandages could also have a major application in the
treatment of long-term skin damage caused by pressure sores
and ulcers, circulation problems, or conditions such as
diabetes.
Background
The living
bandage, known commercially as the Myskin™ bandage, has taken ten years to develop, and is the result of a
collaboration between researchers at Sheffield University
and a spin-off biotechnology company called CellTran. Also
described as a biological bandage,
the technique was first reported in a New
Scientist column in 2002.
The key to success was to give the specially designed
plastic discs a coating which would allow skin cells to
grow, but from which the cells could later be released to
apply to the wound. The successful coating was developed by
adapting the same technique as that used to coat the inside
of drinks cartons! Search
the Web for:
living
bandage
Myskin
biological
bandage
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